The genetics of alcohol intoxication in inbred mice.
The Department of Behavioral Neuroscience, Portland, compared the behaviors of eight inbred mouse strains across 18 variables, using 11 behavioral assays, and gave ethanol (EtOH) as an intoxicant. Genetic influences on behavior and sensitivity to EtOH were pronounced, but strain sensitivities were generally only modestly correlated across tasks. May we expect alcoholism to become a forgotten problem if the tests succeed?
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